Catacombs of Domitilla are near Appian Way and their most ancient nuclei date from the the end of the 2nd century
The catacombs are underground cemeteries that spread for kilometers through a network of subterranean galleries into which numerous tombs were dug. At least until the 4th century, they were used only as a burial grounds, where the cult of the dead was celebrated with liturgical commemorations. Starting from the 6th century and through the 12th century, the catacombs became sanctuaries dedicated to the worship and commemoration of the martyrs.